Measurements and Main Results: Cohort 1 contained 5,460 patients (mortality rate, 14.0% 95% confidence interval, 13.1–15.0), among whom 78.3% had a qSOFA score less than or equal to 1 (mortality rate, 8.3% 95% CI, 7.5–9.1). The predictive accuracy of qSOFA was examined considering only the worst values before the suspicion of infection or sepsis. The primary outcome was in-hospital mortality. Cohort 2 included patients with sepsis (54 hospitals: 24 public and 28 private). Cohort 1 included patients with suspected infection but without organ dysfunction or sepsis (22 hospitals: 3 public and 19 private). Methods: We prospectively collected data from two cohorts of emergency department and ward patients.
Objectives: To assess the predictive accuracy of qSOFA for mortality in Brazil, focusing on sensitivity. Rationale: Although proposed as a clinical prompt to sepsis based on predictive validity for mortality, the Quick Sepsis-related Organ Failure Assessment (qSOFA) score is often used as a screening tool, which requires high sensitivity.
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